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The world's first lab-based tick feeding system for bush ticks, developed by researchers at the University of Melbourne, has transformed the study of ticks and how they transmit disease. The novel, host-free technology reduces the need for animal experiments in tick studies, facilitating more ethical, reproducible research.
Learn more about the advances in brain organoids and what this science could mean for the future.
A study published in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model. The findings provide proof-of-principle for the development of a potential universal donor hPSC line designed to resist immune attack.
In a groundbreaking discovery poised to reshape our understanding of stem cell biology, researchers have unveiled critical insights into the acetylation of Dnmt3L, a key regulatory protein in embryonic stem cells. This new study offers an unprecedented look into how specific acetylation sites impact the protein’s stability and, consequentially, the differentiation potential of stem cells. […]
A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The findings, published today in Molecular Cell, identify a self-clustering mechanism in the Polycomb protein CBX2 that is essential for initiating the formation of gene-repressive condensates and guiding stem cells toward their proper fates.
Craig Crews has incubated some notable biotech companies this century, and hundreds of thousands of blood cancer patients have benefited from a medicine with roots in his Yale lab. His lab’s discoveries, particularly in induced ...
Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) have developed a world-first portable point-of-care test that detects four common sexually transmitted infections at once, in under an hour. The test, which detects syphilis, a high-burden infection, could significantly reduce transmission and improve access to timely treatment.
The planned filing comes amid heightened scrutiny of the FDA’s rare disease stance and a year after Prime deprioritized the program for economic reasons.
A Japanese research team has demonstrated in rat experiments that stem cells from human primary tooth pulp may help treat chronic-phase cerebral palsy. "This is the first animal study to show that stem cell treatment works even after motor deficits have already appeared," said Clinical Professor Yoshiaki Sato of Nagoya University Hospital, the study's corresponding author. The findings are published in the journal Stem Cell Research & Therapy.
Cerebral palsy is a condition usually caused by brain damage before or during birth, resulting in impaired posture and movement.
A groundbreaking study emerging from Japan has unveiled promising advancements in the treatment of cerebral palsy, a debilitating neurological disorder primarily caused by brain injury sustained before or during birth. This condition leads to impaired posture and movement, traditionally without a cure, often diagnosed only after noticeable motor deficits manifest in children. Researchers from Nagoya […]
A research group led by Associate Professor Tetsuya Muramoto from the Faculty of Science, Toho University, has established a CRISPR genome editing technique that enables comparative analysis of the evolution of multicellularity across different species of social amoebae (cellular slime molds). Until now, genetic studies had largely been restricted to a single model species, limiting cross-species comparisons. The work is published in Scientific Reports.
Prime Medicine's application will test an FDA that has promised to speed new gene-editing treatments but has recently spurned some.
A groundbreaking study published in the British Journal of Cancer has unveiled a promising new approach to combat prostate cancer stem cells, which are often implicated in disease recurrence and resistance to conventional therapies. Researchers led by Turnham, French, and Frame have discovered that co-targeting the cellular protein c-FLIP, along with the use of TRAIL […]
Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle remains: real muscle is not just a mass of cells.
In a groundbreaking stride for regenerative medicine, researchers at Xi’an Jiaotong University have unveiled a revolutionary technique that harnesses electrohydrodynamic (EHD) bioprinting to produce living skeletal muscle tissues with unprecedented cellular alignment. This innovation promises to bridge a critical gap that has long stymied tissue engineering: replicating the intricate internal structure of real muscle, where […]
The FDA has allowed Intellia to restart a Phase 3 study of a gene editing therapy for a heart disease caused by misfolded proteins, lifting a hold that was ordered after a patient in the ...
Aging muscles heal more slowly after injury — a frustrating reality familiar to many older adults. A new
Gene-edited crops will face a High Court test in May as campaigners challenge the government’s decision to ease regulation of certain geneti...
CRISPR Therapeutics AG (NASDAQ:CRSP) is one of the top gene therapy stocks to buy according to hedge funds. On February 17, Morgan Stanley lifted the price target on CRISPR Therapeutics AG (NASDAQ:CRSP) to $33 from $32 and maintained an Underweight rating on the shares. The firm stated that it refreshed its estimates on the stock […]
Chinese scientists have used a cutting-edge gene-editing tool to correct a DNA mutation responsible for cognitive and behavioural problems – a move that could eventually lead to the development of new autism therapies. In lab tests, mice that had been engineered to have the mutation showed a striking change in their behaviour, such as the way they interacted with other mice, after being given an injection to introduce the edited genes. The Shanghai-based research team is looking for ways to...
Scientists at the University of California, Irvine's School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells "flip a switch" to rebuild damaged muscle – a finding that could help address muscle loss linked to aging, injury and widely used weight-loss medications.
In a striking advancement toward understanding the complexities of cellular decision-making, Dr. Gregory Reeves and his team at Texas A&M University have unveiled pivotal insights into the behavior of transcription factors within living cells. Their latest research delves into the multifaceted properties of a protein known as Dorsal, a homolog of the well-studied nuclear factor-κB […]
In a Phase I trial, the treatment appeared to be safe in children with spina bifida.
Frailty can typically only be lessened through lifestyle changes, but a stem cell therapy seems to target the underlying causes of the condition, boosting the mobility of frail older people
In an ongoing phase 1 clinical trial, a patient who was recognized as legally blind was implanted with a 3D bioprinted corneal implant.According to a press release from Precise Bio, the implant, known as PB-001, is manufactured using a robotic 3D biofabrication system, with the aim of improving visual outcomes, lowering complication rates and providing a solution for the global corneal tissue shortage. The implantation of PB-001 marked the world’s first transplant of a cell-based, functional 3D bioprinted cornea, the release said.“This achievement marks a turning point for regenerative
India has the ptoential to become a global leader in equitable gene therapy
The study is now scaling up to do more in utero procedures and evaluate effects on disability as children grow
A new CRISPR-based tool that is directly used on patients' cancer cells can identify genes and regulatory elements driving acute myeloid leukemia (AML), an aggressive blood cancer affecting the bone marrow and blood. This first-of-its-kind approach reveals how individual patient cells respond to genetic changes and makes it easier to identify drug targets and understand why some cancers stop responding to treatment. The findings were published today in Molecular Cell, by researchers from Penn Medicine and Children's Hospital of Philadelphia (CHOP).
Proper differentiation of gonadal somatic cells is crucial for sex determination and the production of sex hormones and gametes, and reconstituting this process in culture would both deepen our understanding of this process and enable the generation of ...
A second milestone for Scribe and Lilly highlights growing confidence in CRISPR as a tool for longer, healthier lives. California-based molecular engineering company Scribe Therapeutics has achieved a second success milestone in its collaboration with Eli Lilly, advancing their shared work on in vivo CRISPR-based medicines for neurological and neuromuscular diseases. It is the latest […] The post Gene editing partnership reaches new in vivo success appeared first on Longevity.Technology.
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they've been trying to engineer a cell that's effective against solid tumors, which account for the vast majority of cancer cases. In a key advance in meeting this "holy grail challenge" in the field of cancer cell therapy, a team of Yale scientists led by geneticist Sidi Chen has revealed how immune cells can be "boosted" to target and eradicate solid tumors.
A new study has overcome a long-standing challenge: how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers from Weill Cornell Medicine, Rockefeller University and collaborating institutions offer a detailed look into these hidden HIV-harboring cells and show that some may be more vulnerable to immune destruction than previously believed.
Hematopoietic stem cells are responsible for generating red blood cells and immune cells. With age, this production of cells becomes dysfunctional in a variety of ways, contributing to the aging of the immune system. For example, production of immune cells becomes biased to myeloid cells at the expense of lymphoid cells, a change that contributes indirectly to the more inflammatory behavior of the aged immune system. Identifying specific mechanisms involved in hemotopoietic aging is the first step on the road to finding ways to reverse these issues. Aged hematopoietic stem cells (HSCs) show diminished capacity of self-renewal, skewed lineage output and compromised proteostasis. Ubiquitin proteasomal systems are critical for maintaining protein homeostasis. We show that the levels of Ube2g1, a E2 ubiquitin-conjugating enzyme likely involved […]
3D bioprinting, in which living tissues are printed with cells mixed into soft hydrogels, or “bio-inks,” is widely
In the relentless quest to address the critical shortage of human organs available for transplantation, xenotransplantation — the transplantation of organs, tissues, or cells between different species — has emerged as a beacon of hope. This revolutionary approach, especially focusing on porcine organ transplants, stands poised to transform the future of organ replacement therapy. Pigs […]
Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.
Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.
In a small lab at the University of California, Santa Cruz, clusters of mouse brain cells have taken on a task normally reserved for computer algorithms: keeping a simulated pole balanced upright. The experiment, which used real biological tissue to tackle a classic test problem in control engineering, shows that...Read Entire Article
In a research greenhouse in eastern China’s Zhejiang province, the tomatoes looked ordinary, but they carried a surprisingly sweet scent – the aroma of buttered popcorn. It was not the result of accidental crossbreeding but a precise surgical edit in the tomato genome, performed by the CRISPR/Cas9 tool. Two genes responsible for suppressing aromatic compounds were simultaneously silenced. Then the tomatoes began to emit the signature scent of premium fragrant rice or fresh buttered...
In an era where the fountain of youth has long been the subject of humanity’s deepest aspirations, a groundbreaking study published in Nature Communications by Zong, Park, Tekin-Turhan, and colleagues advances our understanding of the cellular mechanisms underlying aging and longevity. This research delves into the epigenetic landscape of hematopoietic stem cells (HSCs) derived from […]
A bill that would ban the sale and manufacturing of lab-grown protein in Oklahoma is making its way through the state legislature. Scott Blubaugh is the president of American Farmers & Ranchers and the Oklahoma Farmers Union. He tells Brownfield the measure recently passed out of the Senate Ag and Wildlife Committee. “We very much […] The post Bill to ban lab-grown protein gains momentum in Oklahoma Senate appeared first on Brownfield Ag News.
A groundbreaking clinical trial is testing whether specially engineered stem cells can help the brain restore its own dopamine production in people with Parkinson’s disease. Because the condition is driven by the gradual loss of dopamine-producing cells—leading to tremors, stiffness, and slowed movement—researchers are implanting lab-grown cells directly into the brain’s movement center to replace what’s been lost.
Today, we're joined by Professor Matthew Wood, a leading figure in neuroscience and RNA-based therapeutics. The post Accelerating rare disease cures with ASOs, gene editing, and AI appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.
Feed additives suit intensive farming systems, but a longer-lasting solution for methane reduction is needed for pasture-raised cattle, says Ruminant BioTech. The post Ruminant BioTech eyes Canada as launchpad for global expansion with $5.6m research program appeared first on AgFunderNews.
In a groundbreaking advance in plant biotechnology, researchers have harnessed a virus-mediated CRISPR/Cas9 gene-editing system to precisely target and modify a key enzyme regulating metabolic pathways in petunias and lettuce. This innovative approach aimed to disable the inherent molecular “brake” exerted by the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), a critical gatekeeper in the terpenoid […]
Scientists have long sought to understand why some plants are fragrant powerhouses while others remain subtle. Now, a research team from the Hebrew University of Jerusalem has cracked a genetic "bottleneck," using precision gene editing to boost the scent of flowers and the nutritional profile of vegetables. The paper is published in the International Journal of Molecular Sciences.
In the ever-evolving landscape of genome editing, a groundbreaking discovery has emerged from the depths of bacterial immune defense mechanisms, promising to revolutionize the fidelity of CRISPR-Cas9 technologies. Researchers have unveiled a naturally occurring modification in CRISPR RNAs that dramatically enhances the specificity of the widely-used Streptococcus pyogenes Cas9 (SpCas9) enzyme. This innovation, which harnesses […]
A research lab at the University of Caen Normandy (France) has succeeded in making cartilage using decellularized apples.
In a groundbreaking advance poised to reshape the future of genetic medicine, UCLA scientists have unveiled a novel lipid nanoparticle-based gene editing technology capable of precisely inserting a full-length healthy gene into human airway cells. This innovation marks a pivotal leap toward universal gene therapy solutions that transcend the limitations imposed by the vast array […]
Is there room for more Alzheimer’s antibody therapies on the market? Korsana Biosciences' investors think so.
Antibiotic resistance is racing toward a global crisis, with “superbugs” projected to cause over 10 million deaths annually by 2050. Now, scientists at UC San Diego have unveiled a powerful new CRISPR-based tool that doesn’t just fight resistant bacteria—it can actively strip away their drug resistance. Inspired by gene drives used in insects, the technology spreads a genetic “fix” through bacterial populations, even inside stubborn biofilms that shield microbes from antibiotics.
Researchers have demonstrated that lipid nanoparticles can package and deliver an entire therapeutic gene along with gene-editing machinery - a combination of large, complex components that non-viral carriers haven't been able to handle before.
The self-spreading CRISPR tool increased editing efficiency roughly three-fold compared to older versions. The post Souped-Up CRISPR Gene Editor Replicates and Spreads Like a Virus appeared first on SingularityHub.
UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory model of cystic fibrosis and establishing a potential new path toward mutation-agnostic gene therapy for inherited lung diseases.
UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory model of cystic fibrosis and establishing a potential new path toward mutation-agnostic gene therapy for inherited lung diseases.
Wellbeing International Foundation backs cell-free regenerative therapy aimed at restoring the body’s repair language. For years, regenerative medicine was obsessed with the hardware-store approach – the idea that if a part is worn out, you simply swap it. New cells for old tissue, fresh grafts for failing organs. It seemed an easy win, but there […] The post The shift from stem cells to signals appeared first on Longevity.Technology.
The Canadian government's recent approval of the first gene-edited animal to enter the food system has reignited debates over whether foods produced using genetic engineering techniques should be labeled.
Researchers have built a realistic human mini spinal cord in the lab and used it to simulate traumatic injury. The model reproduced key damage seen in real spinal cord injuries, including inflammation and scar formation. After treatment with fast moving “dancing molecules,” nerve fibers began growing again and scar tissue shrank. The results suggest the therapy could eventually help repair spinal cord damage.
In a groundbreaking study, scientists at Johns Hopkins University have made significant strides in our understanding of retinal development and its implications for vision health. This research reveals critical interactions between vitamin A derivatives, specifically retinoic acid, and thyroid hormones during early fetal development in humans, providing new insights into how our eyes develop the […]
Sales of Casgevy, a gene-edited treatment developed with CRISPR Therapeutics, more than tripled compared to the third quarter, a performance analysts saw as a bright spot in Vertex's report.
Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found. The findings could upend decades of conventional understanding of how the eye grows light-sensing cells and could inform new research into treatments for macular degeneration, glaucoma, and other age-related vision disorders. Details of the study, which used lab-grown retinal tissue, are published today in Proceedings of the National Academy of Sciences.
Acute myeloid leukemia (AML) is an aggressive form of blood cancer. It affects people of all ages but is most common in those over 65. Around 150 people are diagnosed with the disease each year in Norway. Men are affected slightly more often than women. Fewer than 5 in 100 patients over the age of 65 survive.
The idea of self-amplifying gene editing is to get cells to pass on packages of CRISPR machinery to their neighbours, boosting the effect
A group of European venture capital firms is banding together to try to improve the funding landscape for biotech startups.
Recent developments in artificial intelligence, genomic analysis and CRISPR gene editing are contributing to a new phase of biological innovation led by firms such as Recursion Pharmaceuticals. AI‑driven pattern recognition is emerging as a foundational tool for accelerating gene discovery and CRISPR‑based technologies across health and materials science. The press release highlights expanded access to […] The post AI, genomics and CRISPR signal a new phase of biological innovation appeared first on Longevity.Technology.
Scientists are testing an entirely new way to fight heart disease: a gene-editing treatment that might offer a one-time fix for high cholesterol.
Every year, around 15 million babies worldwide are born before 37 weeks of gestation. Being born preterm can disrupt development, and earlier births increase the risk of life-changing health outcomes. There are currently no treatment options for brain injury that occurs because of preterm birth, but progress has been made thanks to the PREMSTEM project.
In a groundbreaking advancement poised to redefine treatment approaches for devastating spinal cord injuries, researchers at Northwestern University have engineered the most sophisticated human spinal cord organoid model to date. These miniature, lab-grown tissues replicate the complex cellular environment of the human spinal cord, enabling unprecedented insights into injury mechanisms and regenerative therapies. By deploying […]
Singapore’s appetite for alternative meat seems to be waning, with yet another lab-grown meat company biting the dust. Cultivated meat company Avant Proteins is shutting down its Singapore operations, reported a notice on Singapore’s Government Gazette. The seafood cell research company declared on Jan 30 that it was voluntarily winding up its business here due […]
Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date. In a new study, the research team used lab-grown human spinal cord organoids—miniature organs derived from stem cells—to model different types of spinal cord injuries and test a promising new regenerative therapy. The study is published in the journal Nature Biomedical Engineering.
In a groundbreaking study poised to revolutionize the therapeutic strategies for schistosomiasis-associated fibrosis, researchers have unveiled a novel mechanism by which primed mesenchymal stem cells (MSCs) orchestrate the attenuation of fibrotic progression. This discovery, detailed in a recent publication in Cell Death Discovery, elucidates how MSCs, once primed, potentiate macrophage subset switching and enhance efferocytosis […]
The Wisconsin State Senate will vote on Wednesday on legislation that would regulate lab-grown animal cells. Assembly Bill 554 would require the label “lab grown meat” for any food product containing cultured animal cells or animal tissue derived from cultured cells. Jason Mugnaini with Wisconsin Farm Bureau says the state’s ag coalition strongly supports this […] The post Wisconsin Senate to vote on lab-grown protein bill appeared first on Brownfield Ag News.
South Dakota Governor Larry Rhoden has vetoed a bill that would ban cell-cultured protein in the state. House Bill 1077 would make certain kinds of food, like lab-grown protein, illegal to sell in South Dakota by labeling them adulterated food. In a letter to state lawmakers, Rhoden said the bill imposes a permanent ban on lawful, […] The post South Dakota governor rejects lab-grown meat ban, calls for 5-Year study appeared first on Brownfield Ag News.
The human kidney filters about a cup of blood every minute, removing waste, excess fluid, and toxins from it, while also regulating blood pressure, balancing important electrolytes, activating Vitamin D, and helping the body produce red blood cells. This broad range of functions is achieved in part via the kidney's complex organization. In its outer region, more than a million microscopic units, known as nephrons, filter blood, reabsorb necessary nutrients, and secrete waste in the form of urine.
WASHINGTON (AP) — The Environmental Protection Agency on Friday reapproved the weed killer dicamba for use on genetically modified soybeans and cotton, a pesticide that has raised widespread concern over its tendency to drift and destroy nearby crops. The agency said dicamba was critical for farmers who would otherwise have their crops threatened by fast growing weeds. […] The post Trump Administration Approves Weed Killer Dicamba for Two Common Genetically Modified Crops appeared first on Morning Ag Clips.
In nanoscale particle research, precise control and separation have long been a bottleneck in biotechnology. Researchers at the University of Oulu have now developed a new method that improves particle separation and purification.
Cellares, the first Integrated Development and Manufacturing Organization (IDMO), today announced a collaboration with the Stanford Center for Definitive and Curative Medicine (CDCM) and Stanford Innovative Medicines Accelerator (IMA) to automate manufacturing and release testing for gene-edited hematopoietic stem cell (HSC) therapies, expanding the application of Cellares' automation platforms beyond T cell therapies into a new cell modality.
Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of "superbugs" have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050.
Rice University bioengineer Antonios Mikos is part of a team of researchers led by the Wake Forest Institute for Regenerative Medicine awarded up to $24.8 million over five years to help address the nation's growing organ donor shortage by bioprinting on-demand kidney tissues.
Researchers at Texas A&M are pairing a widely used ingredient with advanced medical technology to develop new treatments for chronic conditions. Could something as simple as coffee one day play a role in cancer treatment? Researchers at the Texas A&M Health Institute of Biosciences and Technology think it might. By pairing caffeine with CRISPR, a [...]
Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of "superbugs" have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050.
The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes, within a cell, a very high number of copies of the oncogene appear—tens or even hundreds. This amplification of oncogenes occurs in a significant proportion of solid tumors and may make the tumor more aggressive and prevent the body's defenses from detecting it, contributing to the development of resistance to treatments.
A groundbreaking research initiative spearheaded by a consortium of scientists at the Spanish National Cancer Research Centre (CNIO) and the Innovative Therapies Unit at CIEMAT has unveiled an innovative application of the CRISPR-Cas9 gene-editing technology in the battle against cancer. This pioneering study focuses on the unique vulnerabilities presented by the amplification of oncogenes within […]
HOUSTON – In a groundbreaking initiative, bioengineers at Rice University are embarking on an ambitious project aimed at creating bioprinted kidney tissues to address the acute organ donor shortage in the United States. This collaborative venture, led by Dr. Antonios Mikos, has garnered a staggering funding of up to $24.8 million over five years from […]
Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after injury. For some, however, muscle development goes awry, leading to weakness, delayed motor milestones or lifelong disabilities. New research from the University of Georgia is shedding light on why.
Oceanic ecosystems are increasingly threatened by global warming, which causes coral bleaching, species migration and, through the loss of habitats and biodiversity, food web disruptions on major scales. Also, pollutants such as plastics and other marine debris, wastewater, as well as chemical runoffs, including oil spills, cause major ecosystem disruptions. Importantly, given the interconnectedness of all life on the planet, the deteriorating health of our oceans directly impacts human health and sustenance.
CRISPR Therapeutics (NASDAQ:CRSP) is one of the stocks that should double by 2030. On January 30, Citizens maintained an Outperform rating on CRISPR Therapeutics while reducing the price target from $86 to $80. The firm highlighted that much of the pipeline remains undervalued and noted that the company could begin late-stage development for up to […]
Vertex is running out of time to establish Casgevy as a transformative treatment for sickle cell.
A research team has successfully demonstrated the world's first gene-editing treatment for Leber's hereditary optic neuropathy (LHON). The study was conducted in collaboration with the Seoul National University College of Veterinary Medicine and Edgene Co., Ltd.
In a groundbreaking advancement poised to revolutionize both agricultural biotechnology and regenerative medicine, researchers at the University of Connecticut’s College of Agriculture, Health and Natural Resources have successfully developed a novel line of bovine embryonic stem cells. This pioneering work, helmed by Professor Xiuchun “Cindy” Tian and her team of graduate researchers, demonstrates significant potential […]
Researchers in the College of Agriculture, Health and Natural Resources have developed a novel line of bovine embryonic stem cells, which have significant potential for a variety of new innovations, from lab-grown meat to models for human tissue replacement. This work, led by Xiuchun "Cindy" Tian, professor of biotechnology in the Department of Animal Science, and her former and current graduate students Yue Su, Jiaxi Liu, and Ruifeng Zhao, was published in Stem Cells.
Tomato (Solanum lycopersicum) is undeniably one of the most globally cultivated and consumed vegetable crops, cherished not only for its vivid red hue and broad culinary applications but also for its rich nutritional profile. However, despite its popularity and widespread use, the characteristic aroma of tomato fruits, a critical factor in flavor perception and consumer […]
In recent years, genome editing technologies have achieved remarkable strides, particularly with the advent of CRISPR-Cas9 systems. Among the various methodologies in this field, the utilization of single-stranded DNA (ssDNA) as a homology-directed repair (HDR) template has garnered considerable attention from researchers. A recent study, led by Velangani et al., delves into the complexities of […]
AccurEdit Therapeutics, a startup based in Suzhou, China, has raised $75 million in Series A funding to advance its growing pipeline of CRISPR-based medicines — among the largest rounds on record for a Chinese gene editing ...