BioTech Review

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21.01.2026
01:32 MorningAgClips.com NC State Genome Editing Center’s Tim Kelliher Connects Biotech to Farmers’ Needs

RALEIGH, N.C. — Tim Kelliher, leader of NC State University’s Genome Editing Center for Sustainable Agriculture, finds his motivation — his “why”— in doing research that meets the real-world needs of farmers. Before taking on the challenge of starting a new research enterprise at NC State, Kelliher spent 12 years developing new breeding technologies to accelerate […] The post NC State Genome Editing Center’s Tim Kelliher Connects Biotech to Farmers’ Needs appeared first on Morning Ag Clips.

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20.01.2026
14:10 Wired.com He Went to Prison for Gene-Editing Babies. Now He’s Planning to Do It Again

Chinese scientist He Jiankui wants to end Alzheimer’s and thinks Silicon Valley is conducting a “Nazi eugenic experiment.”

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00:03 Bioengineer.org CRISPR-Powered Protein Labeling Reveals Regulatory Networks

In the ever-evolving frontiers of molecular biology, the dynamic orchestration of gene expression remains a captivating enigma, particularly in the plant kingdom where environmental cues and developmental signals intricately weave together. Transcriptional regulation, pivotal for these processes, hinges on the complex and transient interactions between proteins and DNA, shaping chromatin landscapes to modulate gene activity. […]

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17.01.2026
20:27 Phys.org Two-step genome editing enables creation of full-length humanized mouse models

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory landscapes often diverge, limiting how accurately mouse models can mimic human biology.

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16.01.2026
19:02 GenEngNews.com UC San Diego Launches ARPA-H Project to 3D Bioprint Patient-Specific Human Livers

UC San Diego researchers are leading a $25.8 million ARPA-H–funded effort to 3D bioprint patient-specific, transplantable human livers, aiming to eliminate organ shortages and improve outcomes for liver failure patients. The post UC San Diego Launches ARPA-H Project to 3D Bioprint Patient-Specific Human Livers appeared first on GEN - Genetic Engineering and Biotechnology News.

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15.01.2026
11:53 FarmingUK.com NFU warns gene editing must not be sacrificed in UK-EU trade talks

Advances in gene editing that could shape the future competitiveness of British farming must not be traded away as the UK seeks closer ties ...

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07:30 News-Medical.Net UC San Diego project aims to bioprint patient-specific transplantable human livers

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in the United States wait for a donor organ.

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00:46 Bioengineer.org Advanced CRISPR Diagnostics for Candida auris Resistance

In recent years, the emergence of Candida auris, a multidrug-resistant fungal pathogen, has raised significant alarm in the medical community. This organism not only presents a unique challenge in terms of treatment efficacy but also requires prompt and reliable identification methods to inform clinical decisions. A study emerging from cutting-edge research introduces an innovative technology […]

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00:08 Bioengineer.org Affordable Gold Nanoparticle Platform Enhances Non-Viral Gene Editing

In recent years, the advancement of gene editing technologies has revolutionized the field of genetics, leading to significant breakthroughs in medical research and therapeutic applications. Among these technologies, CRISPR-Cas9 has emerged as a leading contender, offering unprecedented precision and efficiency in gene editing. However, challenges associated with the delivery of CRISPR systems into target cells […]

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14.01.2026
22:44 Phys.org CRISPR–Cas3 genome-editing system holds therapeutic potential

Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

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22:17 News-Medical.Net CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

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21:16 Phys.org A CRISPR fingerprint of pathogenic C. auris fungi for precision diagnostics

Infection with the pathogenic yeast fungus Candida auris (C. auris) can wreak havoc on the health of hospital patients and residents of nursing homes, especially those who are already weakened by other illnesses. The pathogen easily spreads and colonizes surfaces and objects where it can survive for weeks to months, and is often resistant to standard disinfectants.

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15:33 TechExplorist.com This CRISPR system edits DNA on a much bigger scale

A new in vivo genome-editing system. Continue reading This CRISPR system edits DNA on a much bigger scale on Tech Explorist.

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13.01.2026
05:23 Bioengineer.org CRISPR Targets NOTCH2NLC GGC Repeats to Treat NIID

In an unprecedented leap forward for neurogenetics and therapeutic gene editing, researchers have pioneered a strikingly precise CRISPR/Cas9-based strategy to excise pathogenic nucleotide expansions within the NOTCH2NLC gene, heralding new hope for treating neuronal intranuclear inclusion disease (NIID). This debilitating neurodegenerative disorder, characterized by the accumulation of toxic nuclear inclusions and progressive neuronal loss, has […]

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12.01.2026
18:45 TechMeme.com Researchers from Nvidia, Microsoft, and others use AI on 1M+ species to generate potential new gene editing and drug therapies, including AI-designed enzymes (Financial Times)

Financial Times: Researchers from Nvidia, Microsoft, and others use AI on 1M+ species to generate potential new gene editing and drug therapies, including AI-designed enzymes  —  UK's Basecamp Research uses species genomic sequence database to tackle cancers and superbugs  —  An international team including …

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17:10 Bioengineer.org Precision Genome Editing: Targeted In Vivo Delivery Advances

The revolutionary advent of genome editing has ushered in a new era for the treatment of genetic disorders, promising precise correction of mutations at the DNA level. However, despite its transformative potential, one of the most formidable challenges that has constrained its clinical translation is the difficulty of delivering these genome editors specifically to the […]

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11.01.2026
10:58 ScienceDaily.com This wild fruit is getting a CRISPR makeover

Scientists have used CRISPR to give the goldenberry a modern makeover, shrinking the plant by about a third and making it easier to farm. Goldenberries are tasty and nutritious but notoriously unruly, with bushy plants that complicate harvesting. By editing a few key genes and selectively breeding the best-tasting fruits, researchers created new varieties ready for wider cultivation. The approach could speed up how new crops are adapted for a changing climate.

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09.01.2026
16:40 TechnologyReview.com The Download: the case for AI slop, and helping CRISPR fulfill its promise

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How I learned to stop worrying and love AI slop —Caiwei Chen If I were to locate the moment AI slop broke through into popular consciousness, I’d pick the video of rabbits bouncing…

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14:42 TechnologyReview.com A new CRISPR startup is betting regulators will ease up on gene-editing

Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013, calling it the biggest biotech breakthrough of the century. Yet so far, there’s been only one gene-editing drug approved. It’s been used commercially on only about 40 patients, all with sickle-cell disease. It’s becoming clear that the impact of CRISPR…

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14:08 Wired.com Crispr Pioneer Launches Startup to Make Tailored Gene-Editing Treatments

Aurora Therapeutics, cofounded by Nobel Prize–winning scientist Jennifer Doudna, plans to use gene editing and a new FDA regulatory pathway to commercialize treatments for rare diseases.

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14:07 Endpts.com Gene editing pioneers launch first startup focused on custom CRISPR therapies

Last spring, gene editing scientists stunned the world when they created a bespoke CRISPR therapy to fix a unique genetic mutation that left a boy, known as Baby KJ, hospitalized since birth. The treatment stabilized ...

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14:07 StatNews.com STAT+: Key scientist from Baby KJ team launches startup to scale personalized CRISPR medicines

The gene therapy success with Baby KJ, along with a new FDA program, have companies more interested in treating rare disease.

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09:15 Bioengineer.org GAP-43 Gene-Modified Stem Cells Combat Retinitis Pigmentosa

A groundbreaking study has emerged from recent research on retinitis pigmentosa, a degenerative eye disorder that leads to vision loss and affects millions worldwide. The innovative work, conducted by He, Guo, and Su, delves into the potential of gene-modified bone marrow mesenchymal stem cells (BMSCs) to provide protective benefits for those suffering from this eye […]

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05:41 News-Medical.Net Study reveals innate immune barriers to long-term pig kidney transplant survival

Pioneering research led by Brazilians describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant.

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00:43 MedicalXpress.com Research shows how immune system reacts to pig kidney transplants in living patients

Novel research led by Brazilian scientists describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant. This paves the way for the search for therapies that can prevent organ rejection.

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08.01.2026
22:25 Endpts.com Servier launches VC unit focused on European biotech startups

Servier has set up a corporate venture capital unit armed with about €200 million ($232.9 million) at the outset, joining most other large pharma companies in employing the early-stage startup investment model. The move comes ...

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21:27 News-Medical.Net Scientists discover how stem cells navigate and repair brain damage after stroke

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye-called the cornea-can heal from minor scratches within a single day.

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20:28 News-Medical.Net UBC researchers crack code to grow helper t cells from stem cells

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell-known as helper T cells-from stem cells in a controlled laboratory setting.

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16:18 GenEngNews.com Cas12a3 CRISPR System Targets tRNA Without Destroying Host Cell

Researchers report on a CRISPR system known as Cas12a3 that, on recognition of target DNA, is directed to cut the tail off specific tRNAs, halting virus production and spread, while sparing the host cell DNA. The post Cas12a3 CRISPR System Targets tRNA Without Destroying Host Cell appeared first on GEN - Genetic Engineering and Biotechnology News.

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12:21 Bioengineer.org Bidirectional CRISPR Maps GLIS3 Fibrosis Circuit

A groundbreaking study reveals the pivotal role of the transcription factor GLIS3 in orchestrating a fibrotic cell circuit linked to inflammatory and fibrotic tissue remodeling. Employing state-of-the-art bidirectional CRISPR screens combined with RNA sequencing and chromatin immunoprecipitation assays, researchers have delineated a GLIS3-dependent program governing the behavior of inflammatory activated fibroblasts (IAFs), cells crucial to […]

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11:01 Technology.org Why Traditional CRISPR Screens Fail at Scale—and Cell Pools Help

When Bigger CRISPR Screens Start Producing Unreliable Results CRISPR screening was supposed to make functional genomics more reliable.

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10:02 Bioengineer.org Angptl7+ Periosteal Stem Cells Drive Fracture Healing

In a groundbreaking discovery poised to transform the understanding of bone repair mechanisms, researchers have identified a specialized population of stem cells residing in the fibrous layer of the periosteum that plays an instrumental role in sensing inflammation and orchestrating fracture healing. This novel insight, detailed in the recent Cell Research publication by Jiang et […]

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07.01.2026
23:37 Nanowerk.com Beyond gene scissors: New CRISPR mechanism discovered

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are vital for protein production to shut down infected cells.

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21:38 News-Medical.Net CRISPR Cas12a3: A precise tool to halt viral protein production

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

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19:33 Nature.Com Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit

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19:01 Phys.org CRISPR discovery could lead to single diagnostic test for COVID, flu, RSV

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

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06.01.2026
21:28 MedicalXpress.com Flaws in lab-grown heart cells point the way to better treatments

A study led by Maria Carmo-Fonseca at GIMM has helped clarify one of the main limitations of lab-grown heart cells, which are widely used around the world to study heart disease and test new drugs. Although these cells make it possible to investigate the human heart without invasive procedures or animal models, they still fail to fully reproduce the characteristics of real heart cells, which can compromise the accuracy of certain studies.

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04:54 GenEngNews.com CRISPR Screen Uncovers Genes Driving Brain Cell Development, Neurodevelopmental Disorder

With the help of gene editing tools, scientists uncovered hundreds of genes required for brain cell differentiation and implicated one gene, PEDS1, in a severe neurodevelopmental disorder. The post CRISPR Screen Uncovers Genes Driving Brain Cell Development, Neurodevelopmental Disorder appeared first on GEN - Genetic Engineering and Biotechnology News.

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04:24 News-Medical.Net Beer-making leftovers can be transformed into edible scaffolds for lab-grown meat

Yeast left over from brewing beer can be transformed into edible 'scaffolds' for cultivated meat – sometimes known as lab-grown meat – which could offer a more sustainable, cost-effective alternative to current methods, according to a new study from UCL (University College London) researchers.

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03:41 Phys.org Gene editing in Indonesia: Can new biotechnology solve old agricultural problems?

Like other developing countries, Indonesia is facing a familiar dilemma: how to feed a growing population while protecting its extraordinary biodiversity.

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05.01.2026
17:17 Bioengineer.org CRISPR Screens Identify Genes Driving Neuronal Differentiation

In a groundbreaking study published in Nature Neuroscience, researchers have unveiled new insights into the genetic underpinnings of neurodevelopmental disorders (NDDs) by utilizing cutting-edge CRISPR-Cas9 technology. Neurodevelopmental disorders, which encompass a wide spectrum of conditions arising from disrupted brain development, remain largely enigmatic in terms of their molecular and cellular bases. This study leverages genome-wide […]

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15:27 SeekingAlpha.com Cathie Wood's moves entering 2026: bets on gene-editing and genomics names, adds BEAM, TWST, NTLA

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13:51 ScienceDaily.com This CRISPR breakthrough turns genes on without cutting DNA

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, settling a long-running scientific debate. This gentler form of gene editing could offer a safer way to treat Sickle Cell disease by reactivating a fetal blood gene. Researchers say it opens the door to powerful therapies with fewer unintended side effects.

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13:08 MedicalXpress.com CRISPR screen uncovers hundreds of genes required for brain development

Which genes are required for turning embryonic stem cells into brain cells, and what happens when this process goes wrong? In a new study published today in Nature Neuroscience, researchers led by Prof. Sagiv Shifman from The Institute of Life Sciences at The Hebrew University of Jerusalem, in collaboration with Prof. Binnaz Yalcin from INSERM, France, used genome-wide CRISPR knockout screens to identify genes that are needed for early brain development.

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03.01.2026
10:34 Bioengineer.org Autologous CD133+ Stem Cells Trial for Asherman

In an unprecedented stride toward combatting one of gynecology’s most challenging conditions, a team of researchers has unveiled a groundbreaking therapy employing autologous CD133+ bone marrow-derived stem cells for the treatment of Asherman Syndrome. This innovative approach, examined through a rigorous phase 1/2 clinical trial, promises to redefine therapeutic paradigms by leveraging the body’s intrinsic […]

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02.01.2026
21:29 Medscape.Com Gene-Editing Breakthrough Ends Transfusions for UK Patient

UK doctors have delivered a one-time CRISPR therapy to free a woman with beta thalassaemia from lifelong blood transfusions.

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20:44 News-Medical.Net New method can help better assess precision genome editing technology

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources spent improving CRISPR gene editing technology focus on identifying small off-target sites that pose a safety risk, which is also technically challenging.

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13:59 News-Medical.Net First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

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01.01.2026
01:11 Benzinga.com Cathie Wood's Biotech Trend: Twist, Beam, CRISPR Latest Stock Picks

The massive rotation currently unfolding within ARK Invest suggests that Cathie Wood thinks 2026 will be the year of the genomic revolution.  read more

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31.12.2025
16:04 MedicalDaily.com Gene Editing with CRISPR Technology: Pros, Cons, and the Ethics of Genetic Engineering

CRISPR gene editing offers major medical breakthroughs but raises ethical concerns. Learn its benefits, risks, and societal impact in today's genetic engineering debates.

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14:44 Nanowerk.com The convergence engine: How nanotechnology enables AI, CRISPR, and quantum computing

Explore how nanotechnology acts as the 'Convergence Engine' for AI materials discovery, CRISPR gene therapy delivery, and industrial quantum computing in 2025.

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07:59 InsiderMonkey.com Chardan Maintains A Buy Recommendation On CRISPR Therapeutics AG (CRSP)

CRISPR Therapeutics AG (NASDAQ:CRSP) is among the 12 Best Genomics Stocks to Invest In. TheFly published on November 26, 2025, that Chardan kept its buy recommendation on CRISPR Therapeutics AG (NASDAQ:CRSP) while reducing its price target from $82 to $74. The firm stated that the modification came after revisions to its business model following the […]

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03:27 News-Medical.Net Advancing stem cell regeneration through animal-free culture systems

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection.

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30.12.2025
15:49 InsiderMonkey.com Contrarius Global Equity Fund’s Thoughts on CRISPR Therapeutics’ (CRSP) Gene Editing Therapy

Contrarius Investment Management, an investment management company, released its third-quarter investor letter for the “Contrarius Global Equity Fund”. A copy of the letter can be downloaded here. The fund’s investor class returned 30.9% in the September quarter compared to 7.3% for the benchmark MSCI World Index, including reinvested net income, and 5.5% for the Average […]

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13:52 Nanowerk.com Delivering genome editing components with Lipid Nanoparticles to repair the building blocks of muscles

Scientists have developed a novel approach of genome editing to repair muscle stem (satellite) cells, offering new hope for Duchenne muscular dystrophy (DMD) treatment.

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01:12 SciTechDaily.com CRISPR Breakthrough Could Rewrite Future of Genetic Disease Treatment

A new CRISPR approach can control genes without cutting DNA, opening a safer path for treating genetic diseases. A newly developed form of CRISPR at UNSW Sydney points to a safer way of treating inherited conditions such as Sickle Cell disease. At the same time, it provides clear evidence that chemical markers attached to DNA, [...]

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29.12.2025
20:07 Endpts.com As gene editing tools multiply, the hunt for the final technology continues

John Finn still remembers the twinge of jealousy when he heard someone else had invented a long-sought form of gene editing, one that might finally cure thousands of genetic diseases. At Intellia Therapeutics, Finn had ...

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16:26 SeekingAlpha.com Cathie Wood invests heavily in gene-editing companies, offloads $30 million worth Tesla stock

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13:16 NewScientist.Com Gene-edited babies are the future – but these CRISPR start-ups aren’t

Three start-ups are aiming to create gene-edited babies. Columnist Michael Le Page has no doubt that editing our offspring will one day become routine, but not like this

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28.12.2025
18:06 InsiderMonkey.com Sana Biotechnology Showcases Successful In Vivo Gene Editing of Stem Cells in Nature Publication

Sana Biotechnology Inc. (NASDAQ:SANA) is one of the best emerging technology stocks to invest in. On December 8, Sana Biotechnology announced the publication of groundbreaking preclinical data in the journal Nature Biotechnology. The study, titled “In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles,” details the successful use of […]

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18:06 InsiderMonkey.com CRISPR Therapeutics Reports Strong 90% Response Rate and Lupus Remission in Landmark Zugo-Cel Update

CRISPR Therapeutics (NASDAQ:CRSP) is one of the best emerging technology stocks to invest in. On December 22, CRISPR Therapeutics released a comprehensive clinical update on zugocaptagene geleucel (zugo-cel), formerly known as CTX112. This investigational allogeneic (off-the-shelf) CAR T therapy targets CD19 and is currently being evaluated for both autoimmune diseases and hematologic malignancies. By using […]

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24.12.2025
05:02 Nature.Com Author Correction: Rolling back human pluripotent stem cells to an eight-cell embryo-like stage

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.

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23.12.2025
23:49 Bioengineer.org Mesenchymal Stem Cells: A Path to Reversing Ovarian Aging

In recent years, the field of reproductive medicine has seen groundbreaking advancements, particularly in understanding the impact of age on ovarian function and fertility. At the forefront of this research are mesenchymal stem cells (MSCs), which have shown significant potential in reversing the effects of ovarian aging. A new study conducted by Yao, Chen, Yuan, […]

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16:16 NewScientist.Com How lab-grown lichen could help us to build habitations on Mars

Scientists cultivating partnerships of fungi and algae believe their invention has far-out implications for how we create the buildings of the future

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13:32 IbTimes.co.uk Brazil Advances Lab-Grown Meat with Biopsied Cells and 3D Printing Technology – Is Traditional Slaughter Over?

3D-printed meat in Brazil advances with CELLMEAT 3D project using biopsied cells for lab-grown protein, no slaughter needed

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22.12.2025
19:56 Healio.com Similar outcomes with PRP, mesenchymal stem cells in knee OA

Published results showed umbilical cord-derived platelet-rich plasma provided better short-term pain relief but similar functional outcomes compared with adipose tissue-derived mesenchymal stem cells in early knee osteoarthritis.“We were expecting the adipose tissue to yield superior results, and we were hoping to show that PRP was not as good but still a valid alternative,” Simone Giusti, MD, in the department of sports traumatology and joint reconstruction surgery at Agostino Gemelli University Hospital IRCCS, told Healio. “The results showed that they are exactly the same

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16:36 InsiderMonkey.com 7 Most Promising Gene Editing Stocks According to Analysts

In this article, we will be taking a look at the 7 Most Promising Gene Editing Stocks According to Analysts.  Gene editing has rapidly evolved into a transformative class of technologies that allow scientists to precisely insert, delete, or modify DNA within living cells. Once confined largely to research labs, the field has entered a clinical […]

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19.12.2025
21:16 MedicalXpress.com Scientists show targeting cancer stem cells can prevent gastric cancer recurrence

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer's tendency to return after treatment. The study also demonstrated that eliminating these cells stops tumors from growing, even in advanced disease that has spread to other organs.

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18:07 Bioengineer.org CRISPR Screens Revolutionize Human Neural Organoids Research

Studying the intricate molecular mechanisms that govern the assembly of the human nervous system has long been one of the most significant challenges in developmental biology and neuroscience. Researchers are continuously seeking a deeper understanding of how the human brain is built and what leads to various neurological disorders. Recent advancements in stem cell technology, […]

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16:05 SciTechDaily.com CRISPR Turns a Little-Known Fruit Into a Big Farming Opportunity

Scientists are using CRISPR to fast-track the domestication of a wild fruit. For roughly 10,000 years, farming communities have improved crops by saving seeds from plants that produced better harvests. By repeatedly choosing varieties with desirable traits such as larger size, better flavor, and greater resilience, people gradually shaped the fruits and vegetables that are [...]

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12:38 Bioengineer.org Unraveling Cancer Stem Cells in Tumor Microenvironments

In a groundbreaking study, researchers led by Shrestha, P., Lee, D., and Giri, A. have unveiled new insights into the genomic landscapes and therapeutic potentials of cancer stem cells (CSCs) within the intricate tumor microenvironment. This pivotal work, published in the Journal of Pharmaceutical Investigations, emphasizes the critical role of CSCs in tumor biology, shaping […]

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18.12.2025
23:36 Phys.org Induced pluripotent stem cells: From dish to freezer and back

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without losing their viability or undifferentiated state after thawing. This marks a significant step for research automation, personalized medicine and drug discovery research.

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16:46 GenEngNews.com Animal-Free Protein and Enzyme Deal Expanded by Dyadic and Fermbox Bio

The Dyadic Applied Solutions agreement will enable Fermbox Bio to manufacture and commercialize a growing portfolio of Dyadic-developed proteins and enzymes using both the Dapibus™ and C1 expression systems. The post Animal-Free Protein and Enzyme Deal Expanded by Dyadic and Fermbox Bio appeared first on GEN - Genetic Engineering and Biotechnology News.

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11:22 Medscape.Com Lab-Grown ‘Tiny Brains’ Mimic and Help ID Brain Disorders

Researchers created pea-sized brain structures from stem cells to study neural firing patterns, correctly identifying bipolar disorder and schizophrenia.

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17.12.2025
17:22 MedicalXpress.com 3D bioprinting offers alternative to animal testing for skin disease research

At TU Wien, researchers are developing three-dimensional (3D) printing techniques that can be used to create living biological tissue—for example, to study skin diseases.

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13:08 Phys.org Spot the males: New gene-editing method could transform mosquito control

Researchers have developed a new "color-coded" genetic method that makes it easy to distinguish male and female mosquitoes. This innovation can help solve a major bottleneck in mosquito control strategies that rely on releasing only sterile males. The approach uses gene editing to produce dark males and pale females, offering a practical and safer alternative to current sex-separation techniques.

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02:12 Phys.org Scientists discover how plant cell walls guide stem cells

Imagine if our bodies could grow new organs throughout our entire lives. Plants do this constantly, thanks to tiny, powerful reservoirs of stem cells. But how do these cells know when to divide, and how do they ensure each division is perfectly oriented to build a leaf, a stem, or a flower?

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15.12.2025
23:39 MedicalXpress.com Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

In a new study, scientists at the Max Planck Institute for Evolutionary Anthropology in Leipzig analyzed the impact of more than 2,000 clinically approved drugs on DNA repair and CRISPR genome editing outcomes. They found compounds that can be used to improve genome editing, molecules that selectively kill cultured cancer cells, and further identified novel roles in DNA repair for two proteins.

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21:06 Bioengineer.org Unlocking the Healing Power of Mesenchymal Stem Cells

In recent years, the therapeutic applications of mesenchymal stem cells (MSCs) have garnered significant attention in the field of regenerative medicine. Researchers have been endeavoring to unearth the hierarchical potential of MSCs in various therapeutic settings, particularly in diseases where traditional treatments fall short. The groundbreaking research published by Pearl, Marleau, and Pacheco sheds light […]

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14.12.2025
05:12 Bioengineer.org Blocking Chaperone-Mediated Autophagy Targets Glioblastoma Stem Cells

In a groundbreaking discovery that could redefine therapeutic approaches to one of the most aggressive brain cancers, glioblastoma, researchers have identified a pivotal cellular process whose inhibition may dismantle the formidable defenses of glioblastoma stem cells while simultaneously rejuvenating the body’s natural anti-tumor immune responses. The study, spearheaded by Li, Sheng, Li, and their colleagues, […]

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13.12.2025
20:19 MedicalXpress.com Chromatin accessibility maps reveal how stem cells drive myelodysplastic syndrome progression

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic syndrome (MDS), however, this balance collapses, leading to abnormal blood cell development and a heightened risk of progression to acute myeloid leukemia.

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10:23 News-Medical.Net Engineering muscle stem cells for sustainable cultured meat production

The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible tissues. Muscle stem cells, or satellite cells, are central to this process due to their ability to regenerate and form muscle fibers.

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02:05 Bioengineer.org Guide to CRISPR-Cas9 Editing in Non-Model Insects

In the expansive realm of genetic research, the advent of CRISPR-Cas9 technology has marked a monumental shift, not only within model organisms but also extending its transformative potential to non-model insects. This transition is particularly significant given the ecological and agricultural importance of these species. The insightful exploration by Ahmed, Zheng, and Hunnekuhl aims to […]

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12.12.2025
22:36 GenEngNews.com CRISPR Streamlines Goldenberry Growth to Enable Large-Scale Farming

High-quality genome assemblies and CRISPR editing were applied to the goldenberry to produce compact, more tractable plants that advance domestication efforts and support this underutilized species’ potential as a scalable global crop. The post CRISPR Streamlines Goldenberry Growth to Enable Large-Scale Farming appeared first on GEN - Genetic Engineering and Biotechnology News.

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21:48 Phys.org A new medium for canine stem cells that doesn't contain any human components

Canine induced pluripotent stem (iPS) cells possess the ability to differentiate into any type of cell, making them a useful tool for investigating common canine diseases and disease states, including those of humans.

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20:22 MedicalXpress.com Lab-grown neural circuits reveal thalamus's key role in cortex development

A Japanese research team has successfully reproduced the human neural circuit in vitro using multi-region miniature organs known as assembloids, which are derived from induced pluripotent stem (iPS) cells. With this circuit, the team demonstrated that the thalamus plays a crucial role in shaping cell type-specific neural circuits in the human cerebral cortex.

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02:26 Bioengineer.org Curcumin Shapes M2 Macrophage Response in Stem Cells

In a recent groundbreaking study, researchers have unveiled the remarkable anti-inflammatory potential of curcumin on rat bone marrow-derived mesenchymal stem cells (MSCs). While inflammation is a natural process essential to healing and defense, chronic inflammation can lead to severe damage and is a cornerstone of many diseases. The study conducted by Daryabor et al. highlights […]

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11.12.2025
18:08 ScienceDaily.com Gene-edited CAR-T cells erase aggressive T-cell leukemia

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves—a long-standing challenge in T-cell–based therapies. Early trial results show deep, long-lasting remissions, including in patients who had exhausted standard treatment options.

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16:21 Bioengineer.org In Vivo CRISPR Uncovers Macrophage Roles in Neuroinflammation

In a groundbreaking new study recently published in Nature Neuroscience, researchers have harnessed the full potential of in vivo CRISPR technology to unveil intricate details of macrophage regulation during neuroinflammation. This pioneering work not only deepens our understanding of how macrophage states influence neurological disease progression but also paves the way for targeted therapeutic interventions […]

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13:22 Bioengineer.org Chaperone-Mediated Autophagy Fuels Muscle Stem Cells, Wanes with Age

In the intricate world of cellular biology, the preservation of proteostasis emerges as a crucial determinant of stem cell functionality and longevity. Recent groundbreaking research published in Nature Metabolism uncovers a pivotal role for chaperone-mediated autophagy (CMA) in sustaining the regenerative capacity of muscle stem cells (MuSCs) throughout the aging process. This discovery sheds new […]

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07:45 Bioengineer.org Advancements in Gene Editing for Skeletal Muscle Disorders

In the ever-evolving realm of genetic engineering, Base Editing (BE) and Prime Editing (PE) are emerging as groundbreaking tools that promise to redefine how we approach genetic conditions, particularly those impacting skeletal muscle. These technologies, which are part of the expansive CRISPR/Cas toolkit, offer unprecedented precision in making genetic modifications. Their ability to precisely edit […]

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10.12.2025
20:55 MedicalXpress.com Uncovering the why behind cleft lip and palate with live imaging and gene editing

Every face is unique. Genetics helps to determine our features, but sometimes genes have errors which, in early fetal development, can result in babies with facial differences such as a cleft lip or cleft palate. If not treated, these craniofacial conditions can have a major impact on a baby's quality of life by interfering with a baby's ability to see, breathe, speak clearly, and avoid ear infections.

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19:09 MedicalXpress.com Genetic modifier of Friedreich's ataxia points toward treatment for devastating disorder

Friedreich's ataxia (FA) is a rare but devastating genetic disorder. Those with the condition are often diagnosed between 5 and 15 years of age and live only into their 30s or 40s. There is no widely approved treatment that modifies the disease, and existing therapies may not be effective for all patients.

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15:23 Bioengineer.org Genome Editing: Transforming Crop Improvement Today and Tomorrow

In the rapidly evolving realm of agricultural biotechnology, genome editing has emerged as a transformative force capable of reshaping our approach to crop improvement. This technology, championed by innovations such as CRISPR-Cas9, allows for precise modifications to an organism’s DNA, which can lead to enhanced traits in crops, including improved resistance to diseases, tolerance to […]

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05:03 News-Medical.Net Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

This study shows that vacancy-engineered MoS₂ nanoflowers drive mitochondrial biogenesis in human mesenchymal stem cells by activating SIRT1–PGC-1α signaling and reducing oxidative stress. These treated cells transfer more functional mitochondria to injured recipient cells, restoring energy metabolism and redox balance in multiple in vitro models.

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09.12.2025
22:43 MedicalXpress.com Growth hormone directly regulates stem cells in bone growth plates, revealing a delicate balance

Researchers at the University of Gothenburg can now demonstrate previously unexplained processes behind growth therapy. It involves hormonal mechanisms at the cellular level, with focus on a sensitive balance between stem cells and growth hormone.

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21:16 MedicalXpress.com Disarming cancer stem cells' shield makes immunotherapy more effective

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of cancer. But that remission is short-lived in some cases, and the cancer can return more resistant than before.

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20:21 News-Medical.Net Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA circulating in the blood.

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18:32 Sens.Org Microfluidic platforms for CRISPR-based biosensing advancing molecular diagnostics from benchtop to point-of-care

Sens. Diagn.DOI: 10.1039/D5SD00176E, Critical Review Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yanping Wang, Huimin Jiang, Yanyin Zhang, Qingran Yang, Yujun Song, Yanfeng GaoThis review highlights recent advances in microfluidics-integrated CRISPR–Cas systems for rapid, sensitive, and portable detection of diverse biomarkers, emphasizing their potential to enable sample-to-answer point-of-care diagnostics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

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16:34 Longevity.technology Sana Biotechnology achieves first in vivo gene editing of human blood stem cells

Sana Biotechnology announced that a paper published in Nature Biotechnology shows its “fusogen” virus‑like particle (VLP) platform successfully achieved in … Continue reading "Sana Biotechnology achieves first in vivo gene editing of human blood stem cells" The post Sana Biotechnology achieves first in vivo gene editing of human blood stem cells appeared first on Longevity.Technology - Latest News, Opinions, Analysis and Research.

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